The Greatest Guide To dihydrocodeine side effects bnf

If a nursing mother is an extremely-speedy metabolizer of codeine, it could lead to your morphine overdose while in the nursing little one and result in very major side effects. For nursing mothers using this medicine:

There's little or no information about using other herbal solutions and dietary supplements with sertraline. It is really impossible to say whether they are safe to take with each other. They're not tested in precisely the same way as pharmacy and prescription medicines.

Prevent using Dihydrocodeine tablets and phone your medical doctor instantly or go to the nearest emergency Section when you observe the below really serious side effects:

If women take this drug during pregnancy, there is often a chance that their newborn infants will expertise neonatal withdrawal syndrome.

the dose and duration of concomitant treatment really should be restricted by your health practitioner. Tell your medical professional about all sedative medicines you might be taking and observe your Medical professionals dose suggestion closely.

Sedative medicines for example benzodiazepines or relevant drugs: The concomitant use of opioids with sedative medicines like benzodiazepines or similar drugs boosts the hazard of sedation, respiratory depression, coma and Demise due to additive CNS depressant outcome. The dose and period of concomitant use need to be restricted (see section four.four).

Central Nervous Technique The principal actions of therapeutic price of dihydrocodeine are analgesia and an antitussive effect (depression on the cough reflex by immediate impact on the cough centre during the medulla). Antitussive effects may well manifest with doses lower than These ordinarily expected for analgesia.

Medsafe is working with sponsors of opioid and serotonergic medicines to update the data sheets with information on this interaction (see MARC’s remarks in this edition of Prescriber Update

The velocity of absorption of paracetamol might be amplified by metoclopramide and domperidone and absorption lessened by cholestyramine.

The analgesic impact of dihydrocodeine seems to become predominantly due to the parent compound. The oral bio availability of dihydrocodeine is click here 20% as a consequence of considerable initial move metabolism.

Gastrointestinal side effects of chlorpheniramine have provided dry mouth and constipation in up to 1-3rd of dealt with patients.

Psychological dependence (addiction) is just not likely to happen when narcotics are utilized for this purpose. Actual physical dependence may perhaps lead to withdrawal side effects if treatment is stopped out of the blue. Even so, critical withdrawal side effects can commonly be prevented by little by little minimizing the dose over a timeframe just before treatment is stopped completely. This medicine is available only under a restricted distribution program called the Opioid Analgesic REMS (Possibility Analysis and Mitigation Method) system. Right before Making use of

• This medicine contains paracetamol. Usually do not take anything else containing paracetamol though getting this medicine. Having a painkiller for headaches far too often or for way too long can make them even worse.

Added support and monitoring may very well be required when prescribing for patients at risk of opioid misuse.